The molecular machinery that normally builds proteins inside cells has now taken on a new role as a "switch." A research team ...

Systematic characterization of terminating ribosomes uncovers sequence features influencing ribosome dynamics at stop codons with direct implications in 3' UTR translation.

Within a cell, DNA carries the genetic code for building proteins. To build proteins, the cell makes a copy of DNA, called mRNA. Then, another molecule called a ribosome reads the mRNA, translating it ...

Led by Northwestern Engineering’s Michael Jewett, researchers created a new version of an engineered tethered ribosome dubbed Ribo-T, which provides a foundation to propel broad, new efforts in ...

The discovery of ribosomes dates back to the 1950s, when George Palade first observed dense particles in the cytoplasm of cells using electron microscopy. These particles were later named "ribosomes" ...

Scientists report a method for stable attachment of peptides to tRNAs, which has allowed them to gain new fundamental insights into ribosome function by determining the atomic-level structures of ...

Inside tiny cellular machines called ribosomes, chains of genetic material called messenger RNAs (mRNAs) are matched with the corresponding transfer RNAs (tRNAs) to create sequences of amino acids ...

He ripped the ribosome open, literally. And, it became an important step in the production of antibiotics. In 2000, using a method known as x-ray crystallography, Venkatraman Ramakrishnan and other ...

In the 1940s, scientists at the recently established National Cancer Institute were trying to breed mice that could inform our understanding of cancer, either because they predictably developed ...