Currently running macOS 10.12.3 beta, I had the same issue through pip as @mlyons-tcc . However, I was able to download the tarball (karulis-pybluez-0.22-71-ga0b226a currently) and install from source ...
一部の結果でアクセス不可の可能性があるため、非表示になっています。
アクセス不可の結果を表示する